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Methods: A 67yearold man visited our memory clinic due to progressive memory declines

10.1016/j.jacc.2017.04.041 40 HeK.YanL.LinS

While the majority of the ALS cases (~9095%) are considered as sporadic (sALS) with unknown cause, ~510% cases involve Mendelian pattern of inheritance of familial gene mutations and are known as familial ALS (fALS) (Renton et al., 2014