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For example, biejia extract could inhibit PI3K/Akt/mTOR signaling in MDA-MB-231 breast cancer cells, attenuating EMT and metastatic behaviors (Yang et al., 2022)

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JAK Inhibition as a Therapeutic Strategy for Inflammatory Bowel Disease

Meanwhile, 25-OHC markedly upregulated cytochrome b5 reductase 1 (CYB5R1) and POR, suppressed GSH expression, and promoted lipid peroxidation, thereby enhancing the sensitivity of IMS32 cells to ferroptosis and aggravating neuroglial injury