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Dysregulation of Type II Transmembrane Serine Proteases and Ligand-dependent Activation of MET in Urological Cancers

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This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol

Retatrutide appears to counteract this effect, maintaining or even improving insulin sensitivity during cycles