does glutathione peroxidase have iron The Selenoprotein 4: From Molecular Mechanisms to Novel Therapeutic Opportunities Ferroptosis regulation in lysosome Lysosomal
Ferroptosis regulation in lysosome Lysosomal iron and cathepsin B contribute to ferroptotic cell death. Lysosomal cyst(e)ine can be mobilized to maintain glutathione synthesis and glutathione peroxidase 4 activity, thereby limiting lipid peroxidation. The role of glutathione peroxidase 4 in neuronal ferroptosis and its therapeutic potential in ischemic and hemorrhagic stroke ScienceDirect Oxidative stress, eryptosis and anemia: a pivotal mechanistic nexus in systemic diseases Bissinger 2019 The FEBS Journal Wiley Online Library Revisiting the role of iron in ferroptosis Ferroptosis in Toxicology: Present and Future
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