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The exclusion criteria were: non - RCT studies (such as observational studies, case reports, reviews, etc.)

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doi: 10.1016/j.abb.2021.108926 169 YanSHuiYLiJXuXLiQWeiH

Nausea and GI upset Nausea and general gastrointestinal discomfort appear sporadically in anecdotal reports, more often mentioned with oral capsule use than with transdermal application in community write-ups