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As a key gene encoding the tumor suppressor protein p16INK4a, CDKN2A exhibits significantly high expression in HPV-positive patients, and its high expression level is significantly associated with longer overall survival (Padhi et al., 2017)

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Specific combinations, such as docetaxel and trametinib, have been investigated in KRAS G12C cases with TP53 co-mutations, which did not improve the treatment efficacy in KRAS-mutant patients, highlighting the challenge for tailored co-mutation-targeted therapies [198]

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Garca-Gimnez, J

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It was evident from a study conducted by DiVincenzo and Kaplan [47] that 70% of MC at the concentration of 50200 ppm which was inhaled got readily absorbed by resting volunteers

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Activation of gamma-globin expression by hypoxia-inducible factor 1alpha

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