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Comparative transcriptomics analyses in livers of mice, humans, and humanized mice define human-specific gene networks

In 2024 the FDA approved a biologics license application (BLA) for the investigational T-cell therapy afamitresgene autoleucel (afami-cel,Tecelra ), targeting MAGE- A4 antigen, in the management of advanced synovial sarcoma (57, 58)