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This ROS-regulating ability positions KARs as key signaling molecules in plant stress responses ( Sapium sebiferum seedlings exposed to salt and osmotic stress, indicating that karrikins help alleviate abiotic stress by boosting the antioxidant defense system

On iron metabolism and its regulation

10.1016/S0006-291X(02)00768-4 68

The cellular effects of this hostile environment depend on factors such as cell type, presence of surface receptors, mechanism of transduction and levels of antioxidants [7]

Importantly, this regulation cascade can be exploited by targeting YBX1 to block AMPK protein synthesis and targeting GLUT1 to induce energy stress, which synergistically blunts tumor growth in vivo