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In the fibrous cap of unstable plaques, 5-hydroxyindoleacetic acid was more prevalent (Seeley et al., 2023)

The main allelic variants of the GST gene that lead to significant changes in protein expression are GSTP1 C341TA114V, GSTT1 null/null genotypes, and GSTM1 and GSTM3 (rs11101992 CC), (rs1571858 GG + GA), and GSTM4 (rs560018 GG)