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The synergy of amyloid 1-42 and oxidative stress in the development of Alzheimers disease-like neurodegeneration of hippocampal cells

Zeng X, Geng W, Zhang Y, Yin J, Xu G, Yu M

[Confidence: High] Intraperitoneal (IP) - The Acute Stress/Repair Trigger: IP delivery behaved like a transient hormetic stressor

As a consequence, methylmalonyl CoA is converted into toxic substances such as methylmalonic acid, resulting in a range of clinical manifestations associated with varying degrees of severity in MMA

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