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2 In treating Type II diabetes, patient psychological aversion to the lifestyle change to daily insulin and GLP-1 injections can delay take up of these highly efficacious molecules

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Diabetes 69 , 313330 (2020)

The genetic correlates relate primarily to variants in the genes coding for transporters controlling plasma UA, yet such presumed functional variants will also influence, through the same proteins, the transport of UA into the brain and subsequently into neurons and glia, as described below

Collins LV, Hajizadeh S, Holme E, Jonsson I-M, Tarkowski A