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Conversely, many commenters agreed with CMS' approach of developing an estimation percentage because this approach would not place unreasonable burden on covered entities and would be preferable to any methodology that requires point-of-sale or retrospective identification by covered entities or pharmacies through the use of a claims-based indicator

(2020) 31:250266.e9

H 2 O 2 and H 2 S are small molecule signal sensors in vivo that play an important role in the pathological and physiological processes of organisms

Evidence has been published that impaired insulin and insulin like growth factor signalling pathways contribute to the cellular mechanisms underlying the pathology of Alzheimers disease [88]

Preclinical experimentations indicate that MTAs have the potential to act as better alternatives compared to conventional non-targeted antioxidants in treating PD