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Li B, Jackson J, Simon MD, Fleharty B, Gogol M, Seidel C, et al

Although neuroinflammation is initially a neuroprotective mechanism, its sustained effect over time can induce a neurotoxic effect, which is directly related to neurodegenerative processes ( 2.2.1 Morphological changes Morphologically, microglia have the ability to adopt different morphotypes depending on their state of activation, from quiescent (branched microglia) to hyperbranched, activated, amoeboid or rod microglia (Li et al., 2019)