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Berberine Mechanism: An active compound in several plants, berberine activates AMP-activated protein kinase (AMPK), which plays a role in energy balance and insulin sensitivity

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Kasi, PM, Rivero, S, Aushev, VN, Langer, N, Wang, CG, Cannon, TL, Berim, L, Feinstein, TM, Grothey, A, McCollom, JW, Kalmadi, S, Zakari, A, Dayyani, F, Gravenor, D, Meyer, JM, Sharif, S, Jurdi, A, Liu, MC, Aleshin, A, Kopetz, S

Moreover, miRNAs are capable of exerting an impact on the efficacy of chemotherapy by regulating the generation of tumor stem cells