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When data were not normally distributed the non-parametric tests such as the Mann-Whitney U-test or KruskalWallis analysis of variance were used

Cellular stress can lead to overwhelming mitochondrial dysfunction eventually triggering its degradation by mitophagy [45, 46], and mitochondrial fission is necessary for this process [46,47,48,49]

In addition to the gut-brain and gut-kidney axes, the gut microbiota systemically communicates through other axes such as the gut-liver (Albillos et al., 2020), gut-heart (Zhao et al., 2023), gut-skin (Sinha et al., 2021), and gut-bone (Zhang et al., 2024) axes, among others

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FeRD, the cellular iron redox imbalance triggered by HMRD plays a detrimental role during the cytokine storm in COVID-19 and its clinical aftermath 27,48,49