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SARS-CoV-2 and Coronavirus Disease 2019: what We Know So Far

COX univariate and multivariate regression analysis showed that, portal tumor thrombus (PVTT) (HR=1.87), neutrophil-to-lymphocyte ratio (HR=1.21), -GGT (HR=1.01), tumor size 5cm (HR=1.7), proportion of effect memory T cells (HR=1.08) and CD8 + PD-1 + TIGIT + TIM-3 + T cells (HR=1.13) were independent risk factors for survival of HCC patients

They have the potential to enable better biological characterisation and matching of clinical cohorts across studies, as well as stratification for clinical trials, and more targeted treatments