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This might be responsible for the low IGF-I levels seen in association with states of insulin resistance, as the metabolic syndrome[301]

It possesses immunosuppressive properties through interference with immunoglobulin E which is a protein essential for allergic reactions

doi:10.1126/science.aax3338

Proc Natl Acad Sci U S A 95:84048409 Biterova EI, Barycki JJ (2009) Mechanistic details of glutathione biosynthesis revealed by crystal structures of Saccharomyces cerevisiae glutamate cysteine ligase