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Importantly, such a status also facilitates the gradual emergence of hepatoprotective effects of traditional Chinese medicines (TCMs), such as Si Miao Formula, Jiangzhi Granules, Liushen Capsules, Chaihu-Shugan Power, Cassiae Semen and Gynostemma, as well as some natural products (NPs), including Costunolide, Coprinus comatus polysaccharide, Antarctic krill oil, Oridonin and Berberine, both at the basic exploration and clinical research levels

To date, although numerous natural compounds have been proposed to alleviate hyperpigmentation, insufficient attention has been focused on potential natural skinwhitening agents and their mechanism of action from the perspective of compound classification

Olesen J, Kiilerich K, Pilegaard H

doi: 10.1080/10715762.2017.1291941

4 Results Figure 1 illustrates the flowchart detailing the patient inclusion and exclusion process