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Further studies have revealed that Lip-1 not only prevents mitochondrial lipid peroxidation but also restores the expression of key molecules involved in ferroptosis regulation, including GSH, GPX4 and ferroptosis suppressor protein 1 (135,136)

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Malabsorption and failure to thrive are also common, and eosinophilic esophagitis was identified in one patient

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This in turn leads to the induction of AP-1-dependent target genes, involved in cell proliferation, DNA repair, and cell death 27