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In the existing study, AZA treatment showed a significant depletion in the activity of hepatic GPx, SOD, and an insignificant reduction in CAT with a highly significant elevation in hepatic MDA level, which exerted severe oxidative stress induced by AZA that proved liver injury

Cytoplasmic Grx1-roGFP2 was not reduced upon the addition of either reduced or oxidized glutathione in both gshA gsiB oppC and gshA oppA gsiC strains

10.1073/pnas.73.8.2599 Proc

Pfeiffer RM, Webb-Vargas Y, Wheeler W, Gail MH (2018) Proportion of US Trends in breast cancer incidence attributable to long-term changes in risk factor distributions