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10.1063/5.0065309 Summary Keywords nasal drug delivery, respiratory transport, in silico modeling, computational fluid dynamics, experimental validation, intranasal spray, viral infections, nasal targets Citation Akash MMH, Lao Y, Balivada PA, Ato P, Ka NK, Mituniewicz A, Silfen Z, Suman JD, Chakravarty A, Joseph-McCarthy D and Basu S (2023) On a model-based approach to improve intranasal spray targeting for respiratory viral infections

Post column-switching, analytes are separated and determined using a guard column (Dionex IonPac SGS, 50 mm 4 mm, i.d.) and an analytical column (Dionex IonPac SCS, 250 mm 4 mm, i.d.) with an isocratic mobile phase comprising 3 mM MSA and 10 % (v/v) acetonitrile, at a flow rate of 1 mL/min

Combining these strategies with traditional treatments for hyperthyroidism, such as antithyroid drugs or radioiodine therapy, may provide a more comprehensive approach to managing GD and GO (140, 145)

These symptoms typically diminish over 48 weeks as tolerance develops