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Mellman, I., Chen, D

The content of succinic acid in samples can be calculated by measuring OD value and standard curve at 555 nm

IGF-I/IGF-IR signaling in osteoclasts Studies of global IGF-I KO mice showed fewer (76% of WT control) and smaller osteoclasts with fewer nuclei in the bone (65), indicating impaired osteoclastogenesis and bone resorption (Figure 2)