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Once I manage to get the dose in the syringe, I find the shot to be uncomfortable and to leave my leg/thigh very sore for usually 24 or more hours

[2] How to Manage Discomfort After B12 Treatment Effective management of post-injection discomfort involves both practical self-care measures and appropriate medical follow-up

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Today, well teach you how to give a B12 injection at home, whether to yourself or to someone else

Masson staining revealed that the collagen fibers in the CaT-ME and CaT groups were more closely arranged and had better order than those of the control group