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This condition can subsequently lead to low-grade systemic inflammation and insulin resistance that is central to metabolic diseases

DOI: 10.1016/s0022- 78

Parsons et al., 2020)

The selectivity advantage is well-supported in animal data and is pharmacologically plausible in humans, but the claim that Ipamorelin does not raise cortisol in humans is extrapolating from rat data rather than reporting a confirmed human finding