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Naithani N, Atal AT, Tilak TVSVGK, Vasudevan B, Misra P, Sinha S (2021) Precision medicine: Uses and challenges

Under oxidative stress, thiol groups of cysteine residues are oxidized to form reversible intramolecular disulfide bonds (SS) and cysteine sulfenic acids (CysSOH) or irreversible products such as sulfinic acids (CysSO 2 H) and sulfonic acids (CysSO 3 H) (Kanemura et al

Proteolytic knockdown of GPX1 is highly consistent with previously documented effects of recombinant SARS-CoV M pro in transfected cells, including increased reactive oxygen species and NF-B activation