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Tools such as BestComboScore [160], DrugComb [161], DrugComboRanker [162], and DeepSynergy [163] have been used to predict drug combinations by employing deep learning (DL) and statistical models

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What none of them has and what the blend as a whole entirely lacks is a single controlled clinical trial of the KLOW combination in humans, an established dose, a pharmacokinetic profile, or approval by any drug regulator for any indication