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77 Conditional Phd2 knockout studies in the hematopoietic system revealed that Phd2 regulates hematopoietic stem cell maintenance under the steady state and stressful conditions

These results indicate that pyridoxine can reduce the severity of dopaminergic neuron loss when administered before MPTP beyond targeting dopamine receptors

These findings highlight the potential of focusing on ghrelin as a treatment for CC, while also emphasizing the need for further research to enhance the efficacy of current pharmaceutical interventions

Fulton MD, Dang T, Brown T

An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering