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Acknowledgments The authors would like to acknowledge the postgraduate students of the Department of Pediatric and Preventive Dentistry, Manipal College of Dental Sciences, Mangalore, who helped in the follow-up of the patients

This dynamic duo consists of: Glutathione: Often called the master antioxidant, Glutathione is a powerful molecule naturally produced by your liver

The development of standardized isolation protocols and stability enhancement methods addresses key challenges in clinical translation

Glutathione's antioxidant prowess serves as a vital defense mechanism, acting against environmental aggressors like UV radiation and pollution

Methods: H69 cholangiocytes, THP1 monocyte cell line and cholangiopathy mouse model (0.1% diethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate [DDC] diet feeding x14d) were used