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In vivo half-life studies In hemizygous human FcRn Tg32 mice, groups of male mice (78 weeks, 21.530.5 g, 45 mice/cage/group) were given IV injection, into the lateral tail-vein, of 1 mg/kg of unfused WT albumin and QMP albumin variants, diluted in DPBS (pH 7.4) (Sigma-Aldrich)

Keywords: glutathione, mitochondria, cholesterol, reactive oxygen species, steatohepatitis, Alzheimer disease INTRODUCTION Glutathione (GSH), the major intracellular thiol compound, is a ubiquitous tripeptide produced by most mammalian cells and it is the main mechanism of antioxidant defense against reactive oxygen species (ROS) and electrophiles

Supports Brain Function: - Glutathione plays a crucial role in brain health, protecting neurons from oxidative damage and supporting cognitive function