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doi: 10.1038/nrmicro2613 136 Muoz-MorenoRMartnez-RomeroCGarca-SastreA

Front Biosci 12:332343 Lalo U, Koh W, Lee CJ, Pankratov Y (2021) The tripartite glutamatergic synapse

Bhat AH, Dar KB, Anees S, Zargar MA, Masood A, Sofi MA, Ganie SA (2015) Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases

Furthermore, propionic acid stimulates enteric neurons to release glutamate, which activates vagal afferents to transmit signals to the CNS, modulating mood-related brain circuits ( Foundation for SCFA production: dietary fiber (especially fructans and galactooligosaccharides) can significantly increase the abundance of Bifidobacterium and Lactobacillus in the gut (124), and these two bacterial groups are the main producers of SCFAs (100102)