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10.1371/journal.pone.0096820 73 DasS.FerlitoM.KentO

EngelmannNBlanes GurdiaNFons EsteveJVienneauDM

J Oxid Med Cell Longev

In terms of fibroblast activity, luteolin has been found to inhibit their proliferation, including that of keloid fibroblasts, by regulating the expression of genes such as FRAT1, CyclinD1, and Bcl-2 and promoting apoptosis through the increased expression of p21 and Bax proteins [241]