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Therefore, in the following sections, we will critically discuss the crosstalk between the circadian molecular clock, which introduces a temporal variable into cellular functions, and NF-B transcription factor that have been reported to act as key molecular nodes integrating inflammation and circadian rhythmicity

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Demethylation (mechanism of methyl groups removal) can occur passively through a loss of maintenance during cell division, or actively through eraser enzymes such as TET enzymes (TET1, TET2, TET3), which are able to transform 5mC groups into 5-hydroxymethylcytosine (5hmC) [13, 30]

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Preparation : The staff ensures everything is readyclean, sterile equipment, and, of course, the glutathione solution