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However, this procedure is not exactly easy: Extracting the follicles can take 610 hours and may require 2 sessions, while transplanting them can take even longer (612 hours)

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With regard to the disruption of 1-carbon cycle leading to the development of SZ, the abnormality in DNA methylation in many loci has been found to relate to brain development, stress response, and mitochondrial function [115]

The TCA cycle, in turn, supports mitochondrial respiration, oxidative phosphorylation, and electron transport, while maintaining redox signaling and biosynthetic pathways essential for cell survival (70, 71)