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Lean rats gained more body weight than obese ones from a high-fibre diet

Interestingly, there are also reports claiming that increase of G6PD activity in DA neurons alleviates MPTP-induced neurotoxicity in mice, and aged animals also demonstrate the neuroprotective effect of G6PD [123]

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10.1038/s41420-024-01863-1 30 JiaqiL.SiqingH.QinW.diZ.BeiZ.JialinY

Second, lower levels of MTHF production mean that the methionine cycle slows down, which can lead to the accumulation of homocysteine