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MEK1/2 inhibitors reverse acute vascular occlusion in mouse models of sickle cell disease

Exercise-induced muscle damage may also be important in interpreting the above data since it is highly variable [172,173,174], a function of training status [175], and known to impair muscle insulin sensitivity [176] as well as glycogen replenishment [177]

however, the regeneration supporting capacity of nerve guidance conduits can be augmented by incorporation of neurotrophic factors, Schwann cells, mesenchymal stem cells or alike 19