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In heterodimeric GST complexes such as those formed by the cytosolic mu and alpha classes, however, the cleft between the two subunits is home to an additional high-affinity nonsubstrate xenobiotic binding site, which may account for the enzymes' ability to form heterodimers

aureus (Mohammed et al., 2020)

This oxidative crisis leads to red blood cell destruction, a key concern in malaria treatment and CSIR NET life sciences exams. Primaquine Mechanism in Hemolysis Primaquine treats Plasmodium vivax relapses but its quinone metabolites like 5,6-POQ generate ROS, oxidizing hemoglobin and GSH

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Rare Systemic Adverse Effects Even though they are rare, some people might experience systemic side effects