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It is imperative to understand the pathophysiology that drives infections

As shown above, mice given an acetaminophen overdose (APAP only) had extremely high liver toxicity (as measured by the level of an enzyme called ALT)

It is produced by every cell of the body, with especially high levels in the liver

As we explained in the CY 2025 PFS proposed rule, the Shared Savings Program's existing financial methodology does not fully account for actions taken to protect the integrity of the Medicare program, or address the impact of improper payments, including improper payments resulting from fraud or similar fault on program calculations