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SLC39A8 gene encoding a metal ion transporter: discovery and bench to bedside

As these pumps translocate structurally-unrelated drugs, their overexpression triggered by exposure of cancer cells to one drug leads to the resistance to several others, thereby conferring a multidrug resistance (MDR) phenotype

To understand the magnitude of gene-to-microbiome regulation, we investigated the effect sizes of the identified regulatory pairs in the three tissues

The fat-soluble extract contains a complex of three flavonolignans: Silybin (Silybin A and Silybin B) the main component with the highest biological activity (5070% of the silymarin content) Silydianin Silychristin These three compounds are collectively referred to as silymarin

Stem Cell Res 30 , 150162 (2018)