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Clinical evidence has also emerged: in a cohort of critically ill children, plasma levels of neuronal guidance protein correlated positively with the production of LXA4, MaR1, and PDX, whereas being inversely associated with ICU length of stay and mortality [293]

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PMID: 15712276

In earlier work, Sekhars group had shown that in healthy adults, the levels of oxidative stress, oxidative damage and glutathione remain stable until people enter their 60s, when oxidative stress and oxidative damage begin to increase and glutathione to decline