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The presence of FAD-binding region and transmembrane hemes enable NOXs to act as an electron-transportation chain that transfers two electrons from cytosolic NADPH to extracellular O 2 , resulting in the generation of O 2

7 Limitations and Potential Risks Despite promising results, certain limitations and risks must be considered: Limited Sample Sizes and Durations: Many clinical studies on AOD 9604 have relatively small sample sizes and short durations, which may affect the generalizability of their findings

The motor will need to provide more than the pump power because there will be losses due to motor inefficiencies

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