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The benzyl alcohol preservative does the primary work of suppression, but lower temperatures reduce the growth rate the preservative must counteract

"It's great the players have been freed [and] I think they've got a great sense of relief over that," he added

Storage: Refrigerate the troches at a cool temperature (36 to 46F) to preserve them for several weeks without degradation

However, there is only one approved drug, setmelanotide for POMC-LEPR deficiency [10], and there is no treatment for other POMC-MC4R pathway-deficient diseases, such as POMC-null, MSH-deficiency, and patients with PWS with obesity