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This ultrahigh delivery efficiency of the modified nanomedicine to the brain could be attributed to the highly specific expression of receptors in the area of inflammation and lack of specific recognition in other tissues

The pharmacokinetic profile of acetaminophen has been demonstrated to be dose proportional in adults following administration of single doses of 500, 650, and 1000 mg

Consistent with this, HIF levels in tumor biopsy samples have been associated with high mortality rates in patients with cancer

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