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In HepG2, LN-2024, and HCT116 cells, the expression of GLS2 facilitates the generation of glutathione in tumor cells, thus enhancing cellular antioxidant function [80]

Studies revealed a positive correlation between increased expression of DNMT1 ( p = 0.015) and menorrhagia, and a positive correlation between increased DNMT3B ( p = 0.043) and the severity of dysmenorrhea (Liu and Guo, 2012)