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Furthermore, while AML blasts generally exhibit high glycolytic capacity, the more immature CD34 + CD38 low/ LSC compartment shows a significantly increased mitochondrial dependence and reduced glycolytic capacity compared to the bulk CD34 + population, particularly in intermediate- and adverse-risk patients [121]

Nunez G, Benedict MA, Hu Y, Inohara N

MS excels at detecting multiple molecules simultaneously as well as structure identification and hence meets the requirements of pathway analysis

Byrnes, Uniformed Services University, UNITED STATES Received: June 27, 2016

OPA1 requires mitofusin 1 to promote mitochondrial fusion