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Heart-healthy diet According to the American Society for Preventive Cardiology, 90 per cent of cardiovascular risk is attributable to nine factors: abnormal blood fats (high cholesterol and triglycerides), smoking, high blood pressure, diabetes, abdominal obesity, psychosocial factors, low consumption of fruit and vegetables, too much alcohol and a lack of regular physical activity (Belardo et al., 2022)

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On the contrary, Nrf2 induction by H 2 O 2 was reported in mammalian cell lines 50

*Correspondence: Chi Wang Ip, [email protected] This article was submitted to Multiple Sclerosis and Neuroimmunology, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers