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[DOI] [PubMed] [Google Scholar] 166.Hanson A.D., Henry C.S., Fiehn O., de Crecy-Lagard V

S5F), followed by immunoprecipitation of whole-cell lysates using a FLAG primary antibody

Mechanistic studies confirmed that the anti-cancer effects operate through a dual mode of action: direct suppression of tumor cell proliferation via PAK4 degradation and potentiation of anti-tumor immunity by remodeling the immune microenvironment, as evidenced by RNA-seq analysis revealing enrichment in immune-related pathways such as TNF signaling and interferon response

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Smart inorganic nanoparticles in nanomedicine: Strategies for synthesis and functionalization