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GABA suppresses the formation of IL-12 by macrophages, and IFN- by CD8 T-cells, underscoring its anti-inflammatory role of reducing cytokine production (87)

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The satellite-cell hypothesis The central hypothesis around MGF is that its transient early expression after muscle injury serves to activate quiescent satellite cells the resident muscle stem cells pushing them into proliferation while delaying their terminal differentiation, thereby expanding the pool of myogenic precursors available for repair before the later, IGF-1Ea-driven phase completes the regeneration