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In recent years, an increasing number of studies have focused on adjunctive therapeutic strategies aimed at further protecting dopaminergic neurons based on existing treatments, delaying disease progression, and improving patients quality of life

Conversely, the Gw pretreated Cls group showed a significant increase in cleaved caspase-3 content and a significant decrease in gastric Bcl-2 content compared to the Cls group

While inhibitors targeting this pathway, such as ruxolitinib, have demonstrated promise in preclinical models, their tissue specificity, long-term safety, and dynamic modulation requirements remain to be thoroughly explored

Conlon M, Poltorack CD, Forcina GC, Armenta DA, Mallais M, Perez MA, et al

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