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hence, it has a vital role in antioxidant defense

doi: 10.3390/plants12051133 38 RenW.ChenL

6, June 2021, p

Therefore, understanding the genes involved in this metabolic rewiring within tumors and their surrounding microenvironment is of critical importance ( Figure 8 In tumor cells exhibiting high rates of aerobic glycolysis, increased expression of GLO-1 appears to be a crucial adaptation, enhancing the detoxification of MG and contributing to resistance against multiple therapeutic agents ( Figure 8 ) ( While direct inhibition of tumor glycolysis has been proposed as a seemingly straightforward strategy to deprive cancer cells of energy (32)