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Glutathione - Synthesis SFRBM Education Program Dickinson et al.5 + NADP NADPH Glutathione Reductase GSSG GSH Glutathione H O H O Peroxidase 2 2 2 LOH LOOH PSSP PSSG PSH Glutathione - redox cycling Glutathione - Synthesis SFRBM Education Program Dickinson et al.6 Glutathione uses and losses The glutathione S-transferases (GST) serve a protective role by adding GSH to a molecule, targeting it for export from the cell

Berk M, Copolov D, Dean O, Lu K, Jeavons S, Schapkaitz I, Anderson-Hunt M, Judd F, Katz F, Katz P, Ording-Jespersen S, Little J, Conus P, Cuenod M, Do KQ, Busha AI: N-acetyl cysteine as a glutathione precursor for schizophreniaa double-blind, randomized, placebo-controlled trial

Cardiac causes of hypoxia in sickle cell disease

With infections, several reports have implicated the role of bacterial pneumonia and typhoid fever for the onset of hemolysis (5658)

A condition of low-grade inflammation has been related to NAFLD, with an abnormal production of cytokines and adipokines, such as interleukin (IL)-6, tumor necrosis factor (TNF)-, IL-1, leptin